Japanese team plans to start iPS cells trial for chronic kidney disease in few years
Chronic kidney disease (CKD) affects a large number of patients in Japan but has few effective treatments to halt its progression. A team including Kyoto University published the results of their research in the international scientific journal “Science Translational Medicine” on April 2, showing that when kidney cells made from human induced pluripotent stem cells (iPS cells) were transplanted into mice with CKD, the decline in kidney function was suppressed.
It is estimated that there are approximately 20 million CKD patients in Japan, and as the condition progresses, some patients may need artificial dialysis or a kidney transplant. The team aims to begin clinical trials within the next few years after confirming the safety of the drug, including its effect on other organs.
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